Seres Therapeutics has built a proprietary discovery and design platform that enables us to understand the dysbiosis associated with specific diseases, and to rationally design tailored therapies to establish a healthy microbiome.
We draw upon the disciplines of systems biology and comparative genomics—as well as our expertise in isolating and characterizing microbes that are historically difficult to cultivate—to create a new class of therapies aimed at establishing a healthy microbiome. We compare a vast trove of human data from relevant disease states with that from healthy individuals to characterize specific microbiome functions that are disrupted in states of dysbiosis.
Our deep understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis. The raw material for this effort is a proprietary library of over 9,000 microbial strain isolates derived from healthy human donors, which provides the building blocks of Ecobiotic® drugs. Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases.[/td_text_with_title]
CAMBRIDGE, Mass., Aug 21, 2015 (BUSINESS WIRE) — Seres Therapeutics, Inc. MCRB, +2.06% a leading microbiome therapeutics platform company, announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to SER-109, an oral therapeutic currently in a Phase 2 clinical trial for the prevention of recurrent Clostridium difficile infection (CDI) […]
InRater hotstock Seres Therapeutical, with a recent BTD status from 12 th of June, hit the Nasdaq in full force today with a 100% increase in marketcap. This is a stock we will be monitoring for possible investment, but being outside of the US we could not, alas, participate in the IPO. We made a […]
Seres Therapeutics, which is developing therapies that replace beneficial bacteria to treat infections, announced terms for its IPO on Tuesday. The Cambridge, MA-based company plans to raise $100 million by offering 6.3 million shares at a price range of $15 to $17. At the midpoint of the proposed range, Seres Therapeutics would command a fully […]